2024

Appel K.S., Nürnberger C., Bahmer T., Förster C., Polidori M.C., Kohls M., Kraus T., Hettich-Damm N., Petersen J., Blaschke S., Bröhl I., Butzmann J., Dashti H., Deckert J., Dreher M., Fiedler K., Finke C., Geisler R., Hanses F., Hopff S.M., Jensen B.E.O., Konik M., Lehnert K., Nunes de Miranda S.M., Mitrov O., Reese J.P., Rohde G., Scherer M., Tausche K., Tebbe J.J., Vehreschild J.J., Voit F., Wagner P., Weigl M., Lemhöfer C., i.A. NAPKON Study Group
Definition of the Post‑COVID syndrome using a symptom‑based Post‑COVID score in a prospective, multi‑center, cross‑sectoral cohort of the German National Pandemic Cohort Network (NAPKON). Infection, Februar 2024 DOI: 10.1007/s15010-024-02226-9

Winnand P., Boernsen K.O., Ooms M., Heitzer M., Vohl N., Lammert M., Hölzle F., Modabber A.
Assessment of the electrolyte heterogeneity of tissues in mandibular bone-infiltrating Head and Neck Cancer using Laser-induced Breakdown Spectroscopy. International Journal of Molecular Sciences, Februar 2024 DOI:10.3390/ijms25052607

Flosdorf N., Böhnke J., de Toledo M.A.S., Lutterbach N., Gómez Lerma V., Graßhoff M., Olschok K., Gupta S., Tharmapalan V., Schmitz S., Götz K., Schüler H.M., Maurer A., Sontag S., Küstermann C., Seré K., Wagner W., Costa I.G., Brümmendor T.B., Koschmieder S., Chatain N., Castilho M., Schneider R.K., Zenke M.
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche. Stemm Cell Reports, Februar 2024 DOI:10.1016/j.stemcr.2023.12.011

El Maachi I., Loewen A., Acosta S., Rütten S., Rodríguez-Cabello J.C., Jockenhoevel S., Fernández-Colino A.
Protein-engineered Elastin Fibers as building blocks for the textile-based assembly of tissue equivalents. Advanced Functional Materials, Februar 2024 DOI:10.1002/adfm.202313204

Cacchi C., Fischer H.J., Wermker K., Rashad A., Jonigk D.D., Hölzle F., Klein M.
New tumor budding evaluation in Head and Neck Squamous Cell Carcinomas. Cancers, Januar 2024 DOI:10.3390/cancers16030587

Klein M., Wermker K., Rashad A., Fischer H.J., Jonigk D., Hölzle F., Cacchi C.
A potential new biomarker in HNSCC: Metastasis suppressor protein 1 (MTSS1). Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Januar 2024 DOI:10.1016/j.oooo.2023.12.795

Görg R., Büttgenbach A., Jakobs J., Kurtoğlu Babayev F.H., Rolles B., Rink L., Wessels I.
Leukemia cells accumulate zinc for oncofusion protein stabilization. Journal of Nutritional Biochemistry, Januar 2024 DOI:10.1016/j.jnutbio.2023.109482

2023

Gonzalez-Rubio J., Le-Trilling V.T.K., Baumann L., Cheremkhina M., Kubiza H., Luengen A.E., Reuter S., Taube C., Ruetten S., Duarte Campos D., Cornelissen C.G., Trilling M., Thiebes A.L.
SARS-CoV-2 particles promote airway epithelial differentiation and ciliation. Frontiers in Bioengineering and Biotechnology, November 2023 DOI:10.3389/fbioe.2023.1268782

Berger M., Maqua H., Lysaja K., Mause S.F., Hindle M.S., Naseem K.M., Dahl E., Speer T., Marx N., Schuett K.
Platelets from patients with chronic inflammation have a phenotype of chronic IL-1® release. Research and Practice in Thrombosis and Haemostasis, Oktober 2023 DOI:10.1016/j.rpth.2023.102261

Görg R., Büttgenbach A., Jakobs J., Babayev F.H.K., Rollles B., Rink L., Wessels I.
Leukemia cells accumulate zinc for oncofusion protein stabilization. The Journal of Nutritional Biochemistry, Oktober 2023 DOI:10.1016/j.jnutbio.2023.109482

Weiskirchen R., Schröder S.K., Weiskirchen S., Buhl E.M., Melnik B.
Isolation of Bovine and Human Milk Extracellular Vesicles. Biomedicines, Oktober 2023 DOI:10.3390/biomedicines11102715

Hubens W.H.G., Maié T., Schnitker M., Bocova L., Puri D., Wessiepe M., Kramer J., Rink L., Koschmieder S., Costa I.G., Wagner W.
Targeted DNA Methylation Analysis Facilitates Leukocyte Counts in Dried Blood Samples. Clinical Chemistry, September 2023 DOI:10.1093/clinchem/hvad143

Kyriakou S., Lubig A., Sandhoff C.A., Kuhn Y., Jockenhoevel S.
Influence of Diameter and Cyclic Mechanical Stimulation on the Beating Frequency of Myocardial Cell-Laden Fibers. Gels, August 2023 DOI:10.3390/gels9090677

Zechendorf E., Beckers C., Frank N., Kraemer S., Neu C., Breuer T., Dreher M., Dahl E., Marx G., Martin L., Simon T.P.
A Potential Association between Ribonuclease 1 Dynamics in the Blood and the Outcome in COVID-19 Patients. International Journal of Molecular Sciences, August 2023 DOI:10.3390/ijms241512428

Chen X., Hao D., Becker N., Müller A., Pishnamaz M., Bollheimer L.C., Hildebrand F., Nourbakhsh M.
Unsaturated Long-Chain Fatty Acids Activate Resident Macrophages and Stem Cells in a Human Skeletal Muscle Tissue Model. Biology, August 2023 DOI:10.3390/biology12081111

Lurje I., Gaisa N.T., Dahl, E., Knüchel-Clarke R., Strnad P., Trautwein C., Tacke F., Neumann U.P., Czigany Z., Lurje G.
Genetic polymorphisms in interleukin-1β (rs1143634) and interleukin-8 (rs4073) are associated with survival after resection of intrahepatic cholangiocarcinoma. Scientific Reports, Juli 2023 DOI:10.1038/s41598-023-39487-7

Bocova L., Hubens W.H.G., Engel C., Koschmieder S., Jost E., Wagner W.
Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis. Clinical Epigenetics, Juni 2023 DOI:10.1186/s13148-023-01521-w

Fotouhi O., Nizamuddin S., Falk S., Schilling O., Knüchel-Clarke R., Biniossek M.L., Timmers H.T.M.
Alternative mRNA splicing controls the functions of the histone H3K27 demethylase UTX/KDM6A. bioRxiv, April 2023 DOI:10.1101/2023.04.20.536794

Sarisoy A., Acosta S., Rodriguez-Cabello J.C., Czichowski P., Kopp A., Jockenhoevel S., Fernández-Colino A.
Bioglues Based on an Elastin-Like Recombinamer: Effect of Tannic Acid as an Additive on Tissue Adhesion and Cytocompatibility. International Journal of Molecular Sciences, April 2023 DOI:10.3390/ijms24076776

2022

Kalmer M., Pannen K., Lemanzyk R.,Wirths C., Baumeister J., Maurer A., Kricheldorf K., Schifflers J., Gezer D., Isfort S., Brümmendorf T.H., Koschmieder S., Chatain N.
Clonogenic assays improve determination of variant allele frequency of driver mutations in myeloproliferative neoplasms. Annals of Hematology, Oktober 2022 DOI:10.1007/s00277-022-05000-9

Winnand P., Boernsen K.O., Bodurov G., Lammert M., Hölzle F., Modabber A.
Evaluation of electrolyte element composition in human tissue by laser-induced breakdown spectroscopy (LIBS). Scientific Reports, September 2022 DOI:10.1038/s41598-022-20825-0

Hao D., Becker N., Mückter E., Müller A., Pishnamaz M., Bollheimer L.C., Hildebrand F., Nourbakhsh M.
In Vitro Model of Human Skeletal Muscle Tissue for the Study of Resident Macrophages and Stem Cells. Biology, Juni 2022 DOI:10.3390/biology11060936

Salimi A., Schroeder K.M., Schemionek-Reinders M., Vieri M., Maletzke S., Gezer D., Masouleh B.K., Appelmann I.
Targeting autophagy increases the efficacy of proteasome inhibitor treatment in multiple myeloma by induction of apoptosis and activation of JNK. BMC Cancer, Juli 2022 DOI:10.1186/s12885-022-09775-y

El Maachi I., Kyriakou S., Rütten S., Kopp A., Köpf M., Jockenhoevel S., Fernández-Colino A.
Silk Fibroin as Adjuvant in the Fabrication of Mechanically Stable Fibrin Biocomposites. Polymers, Mai 2022 DOI:10.3390/polym14112251

Lurje I., Czigany Z., Bednarsch J., Gaisa N. T., Dahl E., Knüchel R., Miller H., Ulmer T. F., Strnad P., Trautwein C., Tacke F., Neumann U. P., Lurje G.
Genetic Variant of CXCR1 (rs2234671) Associates with Clinical Outcome in Perihilar Cholangiocarcinoma. Liver Cancer, April 2022 DOI:10.1159/000521613

Herrlein M. L., Hein S., Zahn T., Mhedhbi I., Raupach J., Husria Y., Benz N. I. Eisert J., Bender D., Haberger V., Hastert F. D., Henss L., Schnierle B. S., Stingl J. C., Dreher M., Hildt E.
Comparative Investigation of Methods for Analysis of SARS-CoV-2-Spike-Specific Antisera. Viruses, Februar 2022 DOI:10.3390/v14020410

Sontag S., Bocova L., Hubens W. H. G., Nüchtern S., Schnitker M., Look T., Schröder K. M., Plümäkers B., Tharmapalan V., Wessiepe M., Kraus T., Kramer J., Rink L., Koschmieder S., Wagner W.
Toward Clinical Application of Leukocyte Counts Based on Targeted DNA Methylation Analysis. Clinical Chemistry, Februar 2022 DOI:10.1093/clinchem/hvac006

2021

Hein S., Benz. N. I., Eisert J., Herrlein M., Oberle D., Dreher M., Stingl J., Budt M., Hildt C., Hildt E.
Comirnaty-Elicited and Convalescent Sera Recognize Different Spike Epitopes. Vaccines, Dezember 2021 DOI:10.3390/vaccines9121419

Hein S., Herrlein M., Mhedhbi I., Bender D., Haberger V., Benz N., Eisert J., Stingl J., Dreher M., Oberle D., Schulze J., Mache C., Budt M., Hildt C., Wolff T., Hildt E.
Analysis of BNT162b2- and CVnCoV-elicited sera and of convalescent sera toward SARS-CoV-2 viruses. European Journal of Allergy and Clinical Immunology, November 2021 DOI:10.1111/all.15189

Olschock K., Han L., de Toledo M. A. S., Böhnke J., Graßhoff M., Costa I. G., Theocharides A., Mauerer A., Schüler H. M., Buhl E. M., Pannen K., Baumeister J., Kalmer M., Gupta S., Boor P., Gezer D., Brümmendorf T. h., Zenke M., Chatain N., Koschmieder S.
CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes. Stem Cell Reports, November 2021 DOI:10.1016/j.stemcr.2021.09.019

Franzen J., Nüchtern S., Tharmapalan V., Vieri M., Nikolić M., Han Y., Balfanz P., Nikolaus M., Dreher M., Brümmendorf T. H., Dahl E., Beier F., Wagner W.
Epigenetic Clocks Are Not Accelerated in COVID-19 Patients. International Journal of Molecular Sciences, August 2021 DOI:10.3390/ijms22179306

Baumeister J., Maié T., Chatain N., Gan L., Weinbergerova B., de Toledo M. A. S., Eschweiler J., Maurer A., Mayer J., Kubesova B., Racil Z., Schuppert A., Costa I., Koschmieder S., Brümmendorf T. H., Gezer D.
Early and late stage MPN patients show distinct gene expression profiles in CD34+ cells. Annals of Hematology, August 2021 DOI:10.1007/s00277-021-04615-8

Tillmann S., Olschok K., Schröder S. K., Bütow M., Baumeister J., Kalmer M., Preußger V., Weinbergerova B., Kricheldorf K., Mayer J., Kubesova B., Racil Z., Wessiepe M., Eschweiler J., Isfort S., Brümmendorf T. H., Becker W., Schemionek M., Weiskirchen R., Koschmieder S., Chatain N.
The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN. Microbial Biotechnology, May 2021 DOI:10.1111/1751-7915.13828

von Stillfried S., Villwock S., Bülow R. D., Djudjaj S., Buhl E. M., Maurer A., Ortiz-Brüchle N., Celec P., Klinkhammer B. M., Wong D. W. L., Cacchi C., Braunschweig T., Knüchel-Clarke R., Dahl E., Boor P.
SARS-CoV-2 RNA screening in routine pathology specimens. Cancers, August 2021 DOI:10.3390/cancers131642108

Hannemann J., Balfanz P., Schwedhelm E., Hartmann B., Ule J., Müller-Wieland d.,, Dahl E., Dreher M., Marx N., Böger R.
Elevated serum SDMA and ADMA at hospital admission predict in-hospital mortality of COVID-19 patients. Science Reports, May 2021 DOI:10.1038/s41598-021-89180-w

Warnat-Herresthal S., Schultze H., Shastry K. L., Manamohan S., Mukherjee S., Garg V., Sarveswara R., Händler K., Pickkers P., Aziz N. A., Ktena S., Tran F., Bitzer M., Ossowski S., Casadei N., Herr C., Petersheim D., Behrends U., Kern F., Fehlmann T., Schommers P., Lehmann C., Augustin M., Rybniker J., Altmüller J., Mishra N., Bernardes J. P., Krämer B., Bonaguro L., Schulte-Schrepping J., De Domenico E., Siever C., Kraut M., Desai M., Monnet B., Saridaki M., Siegel C. M., Drews A., Nuesch-Germano M., Theis H., Heyckendorf J., Schreiber S., Kim-Hellmuth S., COVID-19 Aachen Study (COVAS), Nattermann J., Skowasch D., Kurth I., Keller A., Bals R., Nürnberg P., Rieß O., Rosenstiel P., Netea M. G., Theis F., Mukherjee S., Backes M., Aschenbrenner A. C., Ulas T., Deutsche COVID-19 Omics Initiative (DeCOI), Breteler M. M. B., Giamarellos-Bourboulis E. J., Kox M., Becker M., Cheran S., Woodacre M. S. Goh E. L., Schultze J. L.
Swarm Learning for decentralized and confidential clinical machine learning. Nature, May 2021 DOI: 10.1038/s41586-021-03583-3

Möhlendick B., Schönfelder K., Breuckmann K., Elsner C., Babel N., Balfanz P., Dahl E., Dreher M., Fistera D., Herbstreit F., Hölzer B., Koch M., Kohnle M., Marx N., Risse J., Schmidt K., Skrzypczyk S., Sutharsan S., Taube C., Westhoff T. H., Jöckel K.-H., Dittmer U., Siffert W., Kribben A.
ACE2 polymorphism and susceptibility for SARS-CoV-2 infection and severity of COVID-19. Pharmacogenet. Genomics, 2021 May DOI: 10.1097/FPC.0000000000000436

2020

Fuest M., Boor P., Knuechel R., für die DeRegCOVID, Walter P., Salla S.
Postmortem conjunctival and nasopharyngeal swabs in SARS‐CoV‐2 infected and uninfected patients. Acta Ophthalmologica, August 2020 DOI: 10.1111/aos.14559

Kabbert J, Benckert J, Rollenske T, Hitch T. C. A, Clavel T, Cerovic V, Wardemann H, Pabst O.
High microbiota reactivity of adult human intestinal IgA requires somatic mutations. Journal of Experimental Medicine, Juli 2020 DOI: 10.1084/jem.20200275

Wittenborn J., Weikert L., Hangarter B., Stickeler E., Maurer J.
The use of micro RNA in the early detection of cervical intraepithelial neoplasia. Carcinogenesis, Mai 2020 DOI: 10.1093/carcin/bgaa046

Zechendorf E, O’Riordan C. E, Stiehler L, Wischmeyer N, Chiazza F, Collota D, Denecke B, Ernst S, Müller-Newen G, Coldewey S. M, Wissuwa B, Collina M, Simon T, Schuerholz T, Stoppe C, Marx G, Thiemermann C, Martin L.
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis. JCL Insight, April 2020 DOI: 10.1172/jci.insight.131571

Tomasovic A, Brand T, Schanbacher C, Kramer S, Hümmert M. W, Godoy P, Schmidt-Heck W, Nordbeck P, Ludwig J, Homann S, Wiegering A, Shaykhutdinov T, Kratz C, Knüchel R, Müller-Hermelink H, Rosenwald A, Frey N, Eichler J, Dobrev, El-Armouche A, Hengstler J, G, Müller O. J, Hinrichs K, Cuello F, Zernecke A, Lorenz K.
Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects. Nature Communications, April 2020 DOI: 10.1038/s41467-020-15505-4

Rübben A., Wahl R. U., Eggermann T., Dahl E., Ortiz-Brüchle N., Cacchi C.
Mutation analysis of multiple pilomatricomas in a patient with myotonic dystrophy type 1 suggests a DM1-associated hypermutation phenotype. PLOS One, März 2020 DOI: 10.1371/journal.pone.0230003

Rose M., Bringezu S., Godfrey L., Fiedler D., Gaisa N. T., Koch M., Bach C., Füssel S., Herr A., Hübner D., Ellinger J., Pfister D., Knüchel R., Wirth M. P., Böhme M., Dahl E.
ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer. International Journal of Molecular Sciences, Februar 2020 DOI: 10.3390/ijms21031117

Eduati F, Jaaks P, Wappler J, Cramer T, Merten C. A, Garnett M. J, Saez-Rodriguez J.
Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies. Molecular Systems Biology, Februar 2020 DOI: 10.15252/msb.20188664

Hayer S. H, Liepelt I, Barro C, Wilke C, Kuhle J, Martus P, Schöls L. im Namen der EFACTS Forschungsgruppe
NfL and pNfH are increased in Friedreich's ataxia. Journal of Neurology, Januar 2020 DOI: 10.1007/s00415-020-09722-6

2019

Abedin N, Seeman T, Kleinfeld S, Ruehrup J, Röseler S, Trautwein C, Streetz K, Sellge G.
Fecal Eosinophil Cationic Protein Is a Diagnostic and Predictive Biomarker in Young Adults with Inflammatory Bowel Disease. Journal of Clinical Medicine, November 2019 DOI: 10.3390/jcm8122025

Baumeister J, Chatain N, Hubrich A, Maié T, Costa I. G, Denecke B, Han L, Küstermann C, Sontag S, Seré K, Strathmann K, Zenke M, Schuppert A, Brümmendorf T. H, Kranc K. R, Koschmieder S, Gezer D.
Hypoxia-inducible factor 1 (HIF-1) is a new therapeutic target in JAK2 V617F-positive myeloproliferative neoplasms. Leukemia, November 2019 DOI: 10.1038/s41375-019-0629-z

Mijnes J., Tiedemann J., Eschenbruch J., Gasthaus J., Bringezu S., Bauerschlag D., Maass N., Arnold N., Weimer J., Anzeneder T., Fasching PA., Rübner M., Bruno B., Heindrichs U., Freres J., Schulz H., Hilgers RD., Ortiz-Brüchle N., von Serenyi S., Knüchel R., Kloten V., Dahl E.
SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection. Oncotarget, November 2019 DOI: 10.18632/oncotarget.27303

Sassenberg M., Droop J., Schulz W.A., Dietrich D., Loick S. M., Wiek C., Scheckenbach K., Gaisa N. T., Hoffmann M. J.
Upregulation of the long non-coding RNA CASC9 as a biomarker for squamous cell carcinoma. BMC Cancer, August 2019. DOI: 10.1186/s12885-019-6021-6.

Amoury M., Bauerschlag D., Zeppernick F., Von Felbert V., Berges N., Di Diore S., Mintert I., Bleilevens A., Maass N., Bräutigam K., Meinhold-Heerlein I., Stickeler E., Barth S., Fischer R., Hussain A. F.
Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand. Oncotarget, Juli 2019, DOI: 10.18632/oncotarget.10705.

Schuber C, Allhoff M, Tillmann, Maié T, Costa I. G, Lipka D. B, Schemionek M, Feldberg K, Baumeister J, Brümmendorf T. H, Chatain N, Koschmieder S.
Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F-vs. BCR-ABL-positive cells to interferon alpha. Journal of Hematology & Oncology, April 2019 DOI: 10.1186/s13045-019-0722-9.

Weiskirchen S., Kim P., Weiskirchen R.
Laser Ablation Inductively Coupled Plasma Spectrometry: Metal Imaging in Experimental and Clinical Wilson Disease. Inorganics, April 2019 DOI: 10.3390/inorganics7040054.

Naarmann-de Vries I. S., Sachmann Y., Klein F., Ostareck-Lederer A., Ostareck D. H., Jost E., Ehninger G., Brümmerdorf T. H., Marx G., Röllig C., Thiede C., Crysandt M.
Characterization of acute myeloid leukemia with del(9q) – Impact of the genes in the minimally deleted region. Leukemia Research, Januar 2019 DOI: 10.1016/j.leukres.2018.11.007.

2018

Schulz H., Tator M., Spillner J., Dreher M., Knüchel-Clarke R., Kloten V., Dahl E.
Liquid Biopsy im nicht-kleinzelligen Lungenkarzinom: Die blutbasierte Analyse der ctDNA-Methylierung. Der Pathologe, Oktober 2018 DOI: 10.1007/s00292-018-0536-5.

Langhof, H., Kahrass, H., Illig, T., Jahns, R., & Strech, D.
Current practices for access, compensation, and prioritization in biobanks. Results from an interview study. European Journal of Human Genetics, August 2018 DOI:10.1038/s41431-018-0228-x.

Haase, C., Lethaus, B., Knüchel-Clarke, R., Hölzle F., Cassataro A. Braunschweig T.
Development of a Rapid Analysis Method for Bone Resection Margins for Oral Squamous Cell Carcinoma by Immunoblotting. Head and Neck Pathology, Juni 2018 DOI: 10.1007/s12105-017-0856-4.

Koschmieder S., Brümmendorf T. H.
Biobankinganforderungen aus Sicht des Klinikers. Erfahrungen aus der Hämatologie und Onkologie. Der Pathologe, April 2018, DOI 10.1007/s00292-018-0434-x.

Schlensog M, Magnus L, Heide T, Eschenbruch J, Steib F, Tator M, Kloten V, Rose M, Noetzel E, Gaisa NT, Knüchel R, Dahl E.
Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients. Epigenetics April 2018; DOI: 10.1080/15592294.2016.1229730.

Mijnes J., Veeck J., Gaisa N. T., Burghardt E., De Ruijter T. C., Gostek S., Dahl E., Pfister D., Schmid S. C., Knüchel R., Rose M.
Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer. Clinical Epigenetics The official journal of the Clinical Epigenetics Society, Februar 2018, DOI 10.1186/s13148-018-0447-6.

2017

Kloten V, Rüchel N, Ortiz-Brüchle N, Gasthaus J, Freudenmacher N, Steib F, Mijnes J, Eschenbruch J, Binnebösel M, Knüchel R, Dahl E.
Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR. Oncotarget. 2017 Sep 21;8(49):86253-86263. doi: 10.18632.

Rose M., Meurer S. K., Kloten V., Weiskirchen R., Denecke B., Antonopoulos W., Deckert M., Knüchel R., Dahl E.
ITIH5 induces a shift in TGF‐β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death. Molecular Carcinogenesis, September 2017, DOI: 10.1002/mc.22742.

Woitok M, Klose D, Di Fiore S, Richter W, Stein C, Gresch G, et al.
Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells. Onco Targets Ther. 2017 Jul 6;10:3313-3327.

Lebherz C., Schlieper G., Möllmann J., Kahles F., Schwarz M., Bünsing J., Dimkovic N., Koch A., Trautwein C., Flöge J., Marx N., Tacke F., Lehrke M.
GLP-1 Levels Predict Mortality in Patients with Critical Illness as Well as End-Stage Renal Disease. The American Journal of Medicine, Juli 2017 DOI: 10.1016/j.amjmed.2017.03.010.

Garczyk S, Klotz N, Szczepanski S, Denecke B, Antonopoulos W, von Stillfried S, Knüchel R, Rose M, Dahl E.
Oncogenic features of neuromedin U in breast cancer are associated with NMUR2 expression involving crosstalk with members of the WNT signaling pathway. Oncotarget. 2017 May 30;8(22):36246-36265. doi: 10.18632/oncotarget.16121.

2016

Martin L., Horst K., Chiazza F., Oggero S., Collino M., Brandenburg K., Hildebrand F., Marx G., Thiemermann C., Schuerholz T.
The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis. Scientific Reports, November 2016 DOI: 10.1038/srep37277 (2016).

Martin L., Peters C., Heinbockel L., Moellmann J., Martincuks A., Brandenburg K., Schuerholz T
The synthetic antimicrobial peptide 19-2.5 attenuates mitochondrial dysfunction in cardiomyocytes stimulated with human sepsis serum. Innate Immunity, September 2016 DOI: 10.1177/1753425916667474.

Lorsy E., Topuz A. S., Geisler C., Stahl S., Garczyk S., Von Stillfried S., Hoss M., Gluz O., Hartmann A., Knüchel R. Dahl E.
Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer. PLoS One, Juli 2016, DOI: 10.1371/journal.pone.0160077.

Kloten V., Schlensog M.,Eschenbruch J., Gasthaus J., Tiedemann J., Mijnes J., Heide T., Braunschweig T., Knüchel R., Dahl E.
Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients’ Outcome in Basal-Like Breast Cancer. PLoS One, Juli 2016, DOI: 10.1371/journal.pone.0159073.

Dau C., Fliegauf M., Heymut O., Schlensog M., Dahl E., Von Roeyen C. R., Kriz W., Moeller M. J., Braun G. S.
The atypical cadherin Dachsous1 localizes to the base of the ciliary apparatus in airway epithelia. Biochemical and Biophysical Research Communications, Mai 2016, DOI: 10.1016/j.bbrc.2016.04.036.

Schubert C., Allhoff M., Tillmann S., Maié T., Costa I. G., Lipka D. B., Schemionek M., Feldberg K., Baumeister J., Brümmendorf T. H., Chatain N., Koschmieder S.
Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha. Journal of Hematology & Oncology, April 2016 DOI: 10.1186/s13045-019-0722-9.

Dahl E.
Diagnostik: Liquid Biopsy – Status 2016. Deutsches Ärzteblatt 2016; 113(39): [4]; DOI: 10.3238/PersOnko/2016.09.30.01.
Martin L., Koczera R., Simons N., Zechendorf E., Hoeger J., Marx G., Schuerholz T.
The Human Host Defense Ribonucleases 1, 3 and 7 Are Elevated in Patients with Sepsis after Major Surgery—A Pilot Study. International Journal of Molecular Sciences, Februar 2016 DOI: 10.3390/ijms17030294.

2015

Martin L., Peters C., Schmitz S., Moellmann J., Martincuks A., Heussen N., Lehrke M., Müller-Newen G., Marx G., Schuerholz T.
Soluble Heparan Sulfate in Serum of Septic Shock Patients Induces Mitochondrial Dysfunction in Murine Cardiomyocytes. Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Dezember 2015 DOI: 10.1097/SHK.0000000000000462.

Dahl E., Kloten V.
Liquid-biopsy-Analysen mithilfe zellfreier DNA (cfDNA). Möglichkeiten und Grenzen. Der Pathologe, September 2015, DOI: 10.1007/s00292-015-0078-z.

Dötsch M., M.,Kloten V., Schlensog M., Heide T., Braunschweig T., Veeck J., Petersen I., Knüchel R., Dahl E.
Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome. Epigenetics, August 2015, DOI: 10.1080/15592294.2015.1078049.

Martin L, Schmitz S, De Santis R, Doemming S, Haase H, Hoeger J, Heinbockel L, Brandenburg K, Marx G, Schuerholz T.
Peptide 19-2.5 Inhibits Heparan Sulfate-Triggered Inflammation in Murine Cardiomyocytes Stimulated with Human Sepsis Serum. Mai, PLOS ONE 10(5): e0127584.

Bauerschlag D, Maass N, Leonhardt P, Verburg F. A, Pecks U, Zeppernick F, Morgenroth A, Mottaghy F. M, Tolba R, Meinhold-Heerlein I, Bräutigam K.
Fatty Acid Synthase Overexpression: Target for Therapy and Reversal of Hemoresistance in Ovarian Cancer. Journal of Translational Medicine, Mai 2015 13, 146 - 158.

Garczyk S., Von Stillfried S., Antonopoulos W., Hartmann A., Schrauder M. G., Fasching P. A., Anzeneder T., Tannapfel A., Ergönenc Y., Knüchel R., Rose M., Dahl E.
AGR3 in Breast Cancer: Prognostic Impact and Suitable Serum-Based Biomarker for Early Cancer Detection. PloS One, April 2015 DOI: 10.1371/journal.pone.0122106.

Huth S, Heise R, Vetter-Kauczok C. S, Skazik C, Marquardt Y, Czaja K, Knüchel-Clarke R, Merk H. F, Dahl E, Baron J. M.
Inter-a-trypsin inhibitor heavy chain 5 (ITIH5) is overexpressed in inflammatory skin diseases and affects epidermal morphology in constitutive knockout mice and murine 3D skin models. Experimental Dermatology, März 2015 24, 663–668.

Dahl E, Jung A, Fassunke J, Hummel M, Penzel R, Dietmaier W, Laßmann S.
Chancen und Risiken der blutbasierten molekularpathologischen Analytik zirkulierender Tumorzellen (CTC) und zellfreier DNA (cfDNA) in der personalisierten Krebstherapie. Pathologe, Februar 2015 36, 92–97.

Rose M, Schubert C, Dierichs L, Gaisa N. T, Heer M, Heidenreich A, Knüchel-Clarke R, Dahl E.
OASIS/CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitro. Epigenetics, Januar 2015 9(12), 1626 - 1640.

2014

Hummel M., Rufenach C.
Biomaterialbanken als Grundlage für die Entwicklung genetisch basierter Präventionskonzepte. Bundesgesundheitsblatt, Dezember 2014, DOI: https://doi.org/10.1007/s00103-014-2090-5.

Antony P, Rose M, Heidenreich A, Knüchel-Clarke R, Gaisa N. T, Dahl E.
Epigenetic Inactivation of ST6GAL1 in Human Bladder Cancer. BMC Cancer, Dezember 2014 14, 901.

Kloten V, Rose M, Kaspar S, von Stillfried S, Knüchel-Clarke R, Dahl E.
Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype. Epigenetics, August 2014 9(9), 1290 - 1301.

Huth L, Rose M, Kloubert V, Winkens W, Schlensog M, Hartmann A, Knüchel-Clarke R, Dahl E.
BDNF Is Associated with SFRP1 Expression in Luminal and Basal-Like Breast Cancer Cell Lines and Primary Breast Cancer Tissues: A Novel Role in Tumor Suppression? PLOS ONE July 2014 | Volume 9 | Issue 7 | e102558

Kahles F, Meyer C, Möllmann J, Diebold S, Findeisen H. M, Lebherz C, Trautwein C, Koch A, Tacke F, Marx N, Lehrke M.
GLP-1 Secretion Is Increased by Inflammatory Stimuli in an IL-6–Dependent Manner, Leading to Hyperinsulinemia and Blood Glucose Lowering. Diabetes, Oktober 2014 63, 3221–3229.

2013

Dahl E, Haller F.
Personalized urooncology based on molecular uropathology: what is the future? Urologe A. 2013 Jul;52(7):976-81. doi: 10.1007/s00120-013-3229-y. German.

Kloten V, Becker B, Winner K, Schrauder MG, Fasching PA, Anzeneder T, Veeck J, Hartmann A, Knüchel R, Dahl E.
Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening. Breast Cancer Res. 2013 Jan 15;15(1):R4. doi: 10.1186/bcr3375.